In 1980, Renault's mid-range models received the letter S appended to their model designations. At the same time, the color scheme changed to yellow and black. However, the 751S was already introduced in the old colors the previous year. In the S models, the engines’ torque was increased. Road speeds were raised to around thirty kilometers per hour, and except for the smallest model, the number of gears was 12+12. Most models had more lifting power and higher hydraulic output than before. For the models 551S and 651S, Renault developed its own driven front axle. The front axles of the larger four-wheel drives were the same Carraro units with automatic locking differentials as in the MF 600 series. Typical Renault technology still included draft control and dry disc brakes.

The S series was thus a minor update of the lineup introduced in 1974. Sales-wise, the aging lineup clearly lagged behind the late 1970s figures in the 1980s. Before the introduction of new smaller model series, in 1985 the 521S was still brought to market, which had a 2.8-liter engine, 52 hp power, and 2990 kg lifting capacity. To meet the needs of fruit and wine cultivation, Renault offered Carraro tractors as a continuation of its own models based on designs from the 1960s.

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