The fourth generation of the S-series, announced in the fall of 2013, brought updates to the appearance and increased engine power. The Stage 4 emission standard-compliant engine now featured exhaust gas recirculation (EGR) in addition to urea injection. With two turbos, the S374 achieved full 400 hp of additional power and 1600 Nm of torque. The extra power was available at transport speeds and through Voa. One of the turbos was equipped with an electronically controlled wastegate. The hydraulic output was now specified at 205 l/min.

In the summer of 2017, the S394 and a new interface with SmartTouch displays were introduced. LFTN engines compliant with the Euro 6 emission standard for heavy vehicles came into effect at the beginning of 2019. At the same time, new steps, more storage space for tools, and new rear lights were introduced, among other things.

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